Alibius is a jealous old doctor who is in charge of a private lunatic asylum. He is married to Isabella, a woman much younger than himself, and he is worried that when he is away another man may usurp his position. He therefore instructs his servant Lollio to prevent any of the visitors to the asylum, who may include young nobleman who come to gawk at the inmates, from seeing Isabella.

Alibius means "He who is Elsewhere" and Alibius is usually Elsewhere when his wife is on stage.

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